Research Technician (Computational) - Flavell Lab Job at Howard Hughes Medical Institute (HHMI), Cambridge, MA

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  • Howard Hughes Medical Institute (HHMI)
  • Cambridge, MA

Job Description

The Flavell Lab at MIT in Cambridge, Massachusetts is seeking a Research Technician to join our team. Our lab studies how neural circuits generate complex behaviors in freely behaving animals using computational analysis, deep learning, and calcium imaging–based approaches. We work primarily with the model system C. elegans and apply both computational and experimental methods to uncover fundamental principles of brain function. For more information about the Flavell Lab, please visit: Steven – Flavell Lab

About the Role

We are seeking a motivated and creative researcher to participate in computational analysis and modeling of population neural activity. The goal of this work is to understand how neural circuits drive behaviors such as navigation and state-dependent responses. This role involves deep learning–based data processing of calcium imaging recordings, high-dimensional data analysis, and computational modeling that links neural activity to behavior. For interested candidates, there is also an optional opportunity to participate in wet-lab imaging experiments. This position is designed for someone excited about contributing original scientific insights rather than performing routine or procedural tasks.

Application Instructions

To apply, please submit your resume with your GPA clearly listed at the top . Applicants should also include 2–3 professional or academic references .

What We Provide

  • Hands-on experience in a dynamic and immersive research environment.

  • Opportunities for authorship on scientific publications.

  • Direct mentorship and formalized professional development support.

  • Conference participation, including attendance at national and internal scientific meetings.

  • Extensive practice with public speaking through lab meetings, presentations, and collaborative discussions.

  • Additional technical training that strengthens readiness for advanced research roles or positions in industry.

  • A supportive and collaborative team committed to fostering your growth as a researcher.

What You’ll Do

  • Process calcium imaging data using GPU-based software packages, custom-trained neural networks, and related tools.

  • Analyze and interpret high-dimensional neural datasets using systems neuroscience approaches such as neural networks, Bayesian inference, and decoding/encoding methods.

  • (Optional) Conduct in vivo calcium imaging experiments in C. elegans to study how neural circuits generate behavior.

  • Engage in creative, hypothesis-driven research contributing to lab discoveries and broader neuroscience insights.

  • Assist with lab management, organization, equipment maintenance, and safety compliance.

What You Bring

  • Bachelor’s degree in computer science, engineering, neuroscience, biology, mathematics, or a related field.

  • Proficiency in Python or Julia (Matlab preferred) and strong debugging skills.

  • Experience using GitHub for version control and organizing/publishing software packages.

  • Familiarity with core data structures, algorithms, and some exposure to parallel or distributed computing.

  • Strong quantitative and critical-thinking abilities demonstrated through coursework or research.

  • Basic familiarity with biology or neuroscience.

  • Excellent oral and written communication skills, with the ability to analyze data and present it for publication.

  • A highly motivated, organized, and creative mindset, with the ability to work effectively in a team and balance immersive research with lab support tasks.

Physical Requirements

Remaining in a normal seated or standing position for extended periods of time; reaching and grasping by extending hand(s) or arm(s); dexterity to manipulate objects with fingers, for example using a keyboard; communication skills using the spoken word; ability to see and hear within normal parameters; ability to move about workspace. The position requires mobility, including the ability to move materials weighing up to several pounds (such as a laptop computer or tablet). Work may involve possible exposure to malodorous vapors, low dose radiation, contamination by toxic chemicals and acids and presence of carcinogenic substances or other hazardous materials.

Persons with disabilities may be able to perform the essential duties of this position with reasonable accommodation. Requests for reasonable accommodation will be evaluated on an individual basis.

Please Note:

This job description sets forth the job’s principal duties, responsibilities, and requirements; it should not be construed as an exhaustive statement, however.  Unless they begin with the word “may,” the Essential Duties and Responsibilities described above are “essential functions” of the job, as defined by the Americans with Disabilities Act.

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Job Tags

Permanent employment, Full time,

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